Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363489 | 0.84 | FFAR1 (0.61) | FFAR1KEAP1FFAR4CA1CA2 | |
| SCHEMBL69746 | 0.81 | FFAR1 (0.81) | FFAR1KEAP1FFAR4LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL25264643 | 0.79 | FFAR1 (0.77) | FFAR1KEAP1FFAR4LMNAL3MBTL1 | |
| SCHEMBL1206896 | 0.75 | FFAR1 (0.65) | FFAR1KEAP1FFAR4LMNAL3MBTL1 | |
| SCHEMBL169770 | 0.75 | FFAR1 (0.79) | FFAR1KEAP1FFAR4LMNAL3MBTL1 | |
| SCHEMBL193318 | 0.75 | FFAR1 (0.79) | FFAR1KEAP1FFAR4CA1CA2 | |
| SCHEMBL1206798 | 0.75 | L3MBTL1 (0.69) | FFAR1KEAP1FFAR4LMNAL3MBTL1 | |
| SCHEMBL9945963 | 0.75 | LPL (0.72) | L3MBTL1CA1CA2 | |
| SCHEMBL3533619 | 0.74 | FFAR1 (0.87) | FFAR1KEAP1FFAR4LMNAL3MBTL1 | |
| SCHEMBL11424035 | 0.74 | FFAR1 (0.71) | FFAR1KEAP1FFAR4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | FFAR1 1083/4885KEAP1 1115/4885FFAR4 1371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.