Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16687428 | 0.78 | ALDH1A3 (0.41) | ALDH1A3TYRERN1SRC | |
| SCHEMBL5370178 | 0.76 | ALDH1A1 (0.39) | ALDH1A3TYRSRC | |
| SCHEMBL27775328 | 0.74 | CA1 (0.43) | ALDH1A3ERN1SRC | |
| SCHEMBL9945910 | 0.73 | TYR (0.36) | TYR | |
| SCHEMBL2006167 | 0.72 | SRC (0.52) | ALDH1A3TYRSRC | |
| SCHEMBL7842559 | 0.72 | ALDH1A3 (0.48) | ALDH1A3TYRERN1SRC | |
| SCHEMBL14477422 | 0.71 | TYR (0.35) | ALDH1A3TYRSRC | |
| SCHEMBL2489643 | 0.71 | ALDH1A3 (0.47) | ALDH1A3TYRSRC | |
| SCHEMBL9270934 | 0.70 | FNTA (0.42) | TYRSRC | |
| SCHEMBL5882232 | 0.70 | ALDH1A3 (0.52) | ALDH1A3TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A3 2559/4885TYR 2328/4885ERN1 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.