Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642006 | 0.85 | ALOX5 (0.50) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL29956903 | 0.85 | ALOX5 (0.50) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL2045141 | 0.78 | ALOX5 (0.65) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL30142113 | 0.78 | ALOX5 (0.65) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL3147510 | 0.77 | ALOX5 (0.51) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL2847505 | 0.77 | ALOX5 (0.51) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL1402620 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL6748588 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL1807920 | 0.75 | NCEH1 (0.53) | ALOX5ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL1807916 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1KDM4EMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALOX5 2253/4885ALDH1A1 4010/4885KDM4E 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.