Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642006 | 1.00 | ALOX5 (0.50) | ALOX5ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL29956003 | 0.87 | CNR1 (0.51) | TSHRL3MBTL1TDP1GAA | |
| SCHEMBL2556411 | 0.86 | NCF1 (0.46) | ALOX5ALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL14393685 | 0.86 | GAA (0.57) | L3MBTL1TDP1GAA | |
| SCHEMBL29951571 | 0.86 | GAA (0.57) | L3MBTL1TDP1GAA | |
| SCHEMBL9946024 | 0.85 | ALOX5 (0.48) | ALOX5ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL29952915 | 0.84 | CNR1 (0.53) | L3MBTL1TDP1GAA | |
| SCHEMBL7675242 | 0.84 | MAPT (0.42) | ALOX5ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL15330334 | 0.83 | KDM1A (0.42) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL15331311 | 0.83 | SLC2A1 (0.49) | ALDH1A1KDM4ELMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |