Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HPD | P32754 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946091 | 0.87 | MAOB (0.50) | MAOBMAOASPHK1KDM4ETSHR | |
| SCHEMBL684282 | 0.87 | MAOB (0.62) | MAOBMAOAKDM4ETSHRBCHE | |
| SCHEMBL15340870 | 0.86 | NPC1 (0.58) | MAOBSPHK1KDM4ETSHRBCHE | |
| SCHEMBL15340853 | 0.86 | MAOB (0.65) | MAOBMAOASPHK1KDM4ETSHR | |
| SCHEMBL9946059 | 0.84 | MAOB (0.55) | MAOBMAOAAPP | |
| SCHEMBL9946061 | 0.84 | MRGPRX4 (0.56) | MAOB | |
| SCHEMBL15472276 | 0.84 | MAOB (0.60) | MAOBMAOANPC1RAB9AAPP | |
| Formaldehyde SCHEMBL27575662 | 0.83 | KMT2A (0.58) | MAOBMAOABCHEKMT2ASMN1; SMN2 | |
| SCHEMBL9946057 | 0.83 | MAOB (0.60) | MAOBMAOAKDM4ETSHRBCHE | |
| SCHEMBL14163878 | 0.82 | MAOA (0.59) | MAOBMAOASPHK1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | MAOB 780/4885MAOA 809/4885SPHK1 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.