Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.62 |
| ▸ | LIPE | Q05469 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631550 | 0.93 | ENPP2 (0.71) | ENPP2LIPELMNAL3MBTL1HTR6 | |
| SCHEMBL2558783 | 0.93 | ENPP2 (0.71) | ENPP2LIPELMNAL3MBTL1HTR6 | |
| SCHEMBL13723490 | 0.87 | ENPP2 (0.58) | ENPP2LIPELMNAL3MBTL1HTR6 | |
| SCHEMBL9946042 | 0.83 | ENPP2 (0.84) | ENPP2LIPEHTR6MAOBMRGPRX4 | |
| SCHEMBL1956146 | 0.81 | LIPE (0.71) | ENPP2LIPELMNAL3MBTL1MRGPRX4 | |
| SCHEMBL29825616 | 0.81 | LIPE (0.71) | ENPP2LIPELMNAL3MBTL1MRGPRX4 | |
| SCHEMBL2558644 | 0.80 | MRGPRX4 (0.52) | ENPP2LIPELMNAHTR6MAOB | |
| SCHEMBL9893416 | 0.79 | LIPE (0.77) | ENPP2LIPELMNAL3MBTL1MAOB | |
| SCHEMBL30631479 | 0.79 | LIPE (0.77) | ENPP2LIPELMNAL3MBTL1MAOB | |
| SCHEMBL2559611 | 0.78 | ENPP2 (0.75) | ENPP2LIPELMNAHTR6MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ENPP2 147/4885LIPE 3056/4885LMNA 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.