Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558238 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL3149374 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL14228414 | 0.80 | MAPT (0.56) | ALDH1A1HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL15872037 | 0.79 | GAA (0.60) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27834056 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL15872010 | 0.77 | MAOB (0.47) | ALDH1A1HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL1200245 | 0.76 | MAOA (0.52) | ALDH1A1HPGDTSHRSMN1; SMN2RAB9A | |
| SCHEMBL9946078 | 0.76 | MAOB (0.56) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2561404 | 0.73 | MRGPRX4 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AFFAR1 | |
| SCHEMBL9946103 | 0.73 | FFAR4 (0.40) | SMN1; SMN2FFAR1FFAR4LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885HPGD 2142/4885TSHR 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.