Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558750 | 0.88 | MRGPRX4 (0.64) | MRGPRX4KDM4EFFAR4IGF1RMET | |
| SCHEMBL15701557 | 0.83 | MRGPRX4 (0.67) | MRGPRX4KDM4EFFAR4IGF1RMET | |
| SCHEMBL12295554 | 0.81 | MRGPRX4 (0.68) | MRGPRX4KDM4EFFAR4RECQLRXRA | |
| SCHEMBL15701532 | 0.81 | MRGPRX4 (0.64) | MRGPRX4KDM4EFFAR4 | |
| SCHEMBL22480871 | 0.76 | MRGPRX4 (1.00) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL9893596 | 0.75 | MRGPRX4 (0.54) | MRGPRX4KDM4EFFAR4RECQLFFAR1 | |
| SCHEMBL9946101 | 0.74 | MRGPRX4 (0.47) | MRGPRX4KDM4EFFAR4RECQLFFAR1 | |
| SCHEMBL2556265 | 0.72 | MRGPRX4 (0.61) | MRGPRX4FFAR4FFAR1 | |
| SCHEMBL12851580 | 0.71 | RXRA (0.57) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL12024746 | 0.71 | MRGPRX4 (0.56) | MRGPRX4KDM4EFFAR4SRCFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | MRGPRX4 243/4885KDM4E 4270/4885FFAR4 1371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.