Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560319 | 0.89 | MRGPRX4 (0.50) | MRGPRX4KDM4ERECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL17236439 | 0.77 | LIPE (0.40) | MRGPRX4KDM4ERECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL12295554 | 0.76 | MRGPRX4 (0.68) | MRGPRX4KDM4ERECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL9946102 | 0.74 | MRGPRX4 (0.62) | MRGPRX4KDM4ERECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL9442078 | 0.74 | MRGPRX4 (0.52) | MRGPRX4KDM4EALDH1A1FFAR4FFAR1 | |
| SCHEMBL2554682 | 0.72 | L3MBTL1 (0.47) | MRGPRX4SMN1; SMN2FFAR4FFAR1LMNA | |
| SCHEMBL15701533 | 0.71 | MRGPRX4 (0.52) | MRGPRX4KDM4ERECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL2556867 | 0.70 | ENPP2 (0.51) | MRGPRX4SMN1; SMN2FFAR4FFAR1LMNA | |
| SCHEMBL9442059 | 0.70 | MRGPRX4 (0.48) | MRGPRX4KDM4ESMN1; SMN2FFAR4FFAR1 | |
| SCHEMBL814457 | 0.70 | KDM4E (0.72) | MRGPRX4KDM4ERECQLSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | MRGPRX4 243/4885KDM4E 4270/4885RECQL 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.