SCHEMBL9946340

SCHEMBL9946340

O=C(Nc1ccccc1)C1CCC1C(=O)Nc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.69
MAPT P10636 4/20 0.67
GAA P10253 3/20 0.67
POLB P06746 3/20 0.65
TDP1 Q9NUW8 2/20 0.65
HPGD P15428 2/20 0.63
RAB9A P51151 3/20 0.62
LMNA P02545 2/20 0.62
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
GFER P55789 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
NPC1 O15118 1/20 0.61
DEGS1 O15121 1/20 0.57
FNTA P49354 1/20 0.57
FNTB P49356 1/20 0.57
HTT P42858 3/20 0.56
NAMPT P43490 1/20 0.56
ALDH1A1 P00352 1/20 0.56
KDM4E B2RXH2 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105931 0.92 MAPT (0.78) L3MBTL1MAPTGAAPOLBTDP1
SCHEMBL10337750 0.92 MAPT (0.78) L3MBTL1MAPTGAAPOLBTDP1
SCHEMBL9944500 0.91 POLB (0.65) L3MBTL1MAPTGAAPOLBTDP1
SCHEMBL11861632 0.88 POLB (0.61) L3MBTL1MAPTGAAPOLBTDP1
SCHEMBL23992767 0.86 SMN1; SMN2 (0.81) L3MBTL1MAPTGAAPOLBTDP1
SCHEMBL18214318 0.86 SMN1; SMN2 (0.81) L3MBTL1MAPTGAAPOLBTDP1
SCHEMBL535321 0.84 L3MBTL1 (0.56) L3MBTL1MAPTGAAPOLBTDP1
SCHEMBL16602956 0.83 POLB (0.56) L3MBTL1MAPTGAAPOLBTDP1
SCHEMBL15706299 0.83 DEGS1 (0.82) MAPTGAATDP1HPGDRAB9A
SCHEMBL501924 0.83 GAA (0.85) MAPTGAAPOLBHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2957575-B1 OPTICALLY ACTIVE POLY(DIPHENYLACETYLENE) COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS OPTICAL ISOMER SEPARATING AGENT NAT UNIV CORP KANAZAWA UNIV (JP) 2017-10-18 EP disclosed
EP-2426492-B1 Separating agent for optical isomer DAICEL CORP (JP) 2017-10-04 EP disclosed
US-9562121-B2 Optically active poly(diphenylacetylene) compound, preparation method therefor, and use thereof as optical isomer separating agent NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2017-02-07 US disclosed
US-9562121-B2 Optically active poly(diphenylacetylene) compound, preparation method therefor, and use thereof as optical isomer separating agent NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2017-02-07 US disclosed
EP-2472255-B1 SEPARATING AGENT FOR OPTICAL ISOMER DAICEL CORP (JP) 2016-05-25 EP disclosed
US-20150376308-A1 OPTICALLY ACTIVE POLY(DIPHENYLACETYLENE) COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS OPTICAL ISOMER SEPARATING AGENT NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2015-12-31 US disclosed
US-20150376308-A1 OPTICALLY ACTIVE POLY(DIPHENYLACETYLENE) COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS OPTICAL ISOMER SEPARATING AGENT NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2015-12-31 US disclosed
EP-2957575-A1 OPTICALLY ACTIVE POLY(DIPHENYLACETYLENE) COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS OPTICAL ISOMER SEPARATING AGENT National University Corporation Kanazawa University (JP) 2015-12-23 EP disclosed
US-9028684-B2 Separating agent for optical isomer DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2015-05-12 US disclosed
EP-1881009-B1 CHITOSAN DERIVATIVE AND METHOD FOR PRODUCING SAME UNIV NAGOYA NAT UNIV CORP (JP) 2015-01-07 EP disclosed
WO-2014126028-A1 OPTICALLY ACTIVE POLY(DIPHENYLACETYLENE) COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS OPTICAL ISOMER SEPARATING AGENT 国立大学法人 金沢大学 (JP) 2014-08-21 WO disclosed
EP-2472255-A1 SEPARATING AGENT FOR OPTICAL ISOMER Daicel Corporation (JP) 2012-07-04 EP disclosed
US-20120149851-A1 SEPARATING AGENT FOR OPTICAL ISOMERS NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2012-06-14 US disclosed
US-20120007011-A1 Separating agent for optical isomer NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2012-01-12 US disclosed
US-7772382-B2 Chitosan derivative and method of producing same NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2010-08-10 US disclosed
US-20090062519-A1 Chitosan Derivative and Method of Producing Same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-05 US disclosed