Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9898559 | 0.92 | PTGES (0.47) | PTGES | |
| SCHEMBL9946780 | 0.92 | PTGES (0.44) | PTGES | |
| SCHEMBL9898794 | 0.90 | PTGES (0.48) | PTGESSCN10A | |
| SCHEMBL9944992 | 0.84 | PTGES (0.40) | PTGES | |
| SCHEMBL9946857 | 0.83 | PTGES (0.39) | PTGES | |
| SCHEMBL9898451 | 0.83 | KDM4E (0.45) | SCN10A | |
| SCHEMBL9897728 | 0.81 | ALDH1A1 (0.40) | SCN10A | |
| SCHEMBL9946613 | 0.81 | PTGES (0.46) | PTGESSCN10A | |
| SCHEMBL9946574 | 0.80 | PTGES (0.46) | PTGES | |
| SCHEMBL9946853 | 0.80 | PTGES (0.46) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | PTGES 3/4885SCN10A 3058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.