Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 18/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946603 | 1.00 | PTGES (0.48) | PTGESS100A4ALDH1A1POLB | |
| SCHEMBL9944935 | 0.88 | RAB9A (0.43) | PTGESS100A4 | |
| SCHEMBL9946737 | 0.87 | PTGES (0.48) | PTGES | |
| SCHEMBL9899126 | 0.87 | PTGES (0.48) | PTGESS100A4 | |
| SCHEMBL9899130 | 0.87 | PTGES (0.48) | PTGESS100A4 | |
| SCHEMBL9899028 | 0.87 | PTGES (0.48) | PTGESS100A4 | |
| SCHEMBL9899024 | 0.87 | PTGES (0.48) | PTGESS100A4 | |
| SCHEMBL9946827 | 0.87 | PTGES (0.48) | PTGESS100A4 | |
| SCHEMBL9899013 | 0.86 | PTGES (0.45) | PTGESALDH1A1POLB | |
| SCHEMBL9899009 | 0.86 | PTGES (0.45) | PTGESALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076673-A1 | 6-AMINO-2-PHENYLAMINO-1H-BENZIMIDAZOLE-5-CARBOXAMIDE- DERIVATIVES AND THEIR USE AS MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |