Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.39 |
| ▸ | CNR1 | P21554 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104256 | 0.82 | MAPK14 (0.38) | CNR2ALDH1A1EGFRGAATRPM8 | |
| SCHEMBL1013248 | 0.78 | CNR2 (0.38) | CNR2CNR1ALDH1A1MAPT | |
| SCHEMBL9891487 | 0.78 | EGFR (0.42) | CNR2CNR1ALDH1A1EGFRGAA | |
| SCHEMBL26457324 | 0.78 | TRPM8 (0.33) | ALDH1A1EGFRGAATRPM8MAPT | |
| SCHEMBL14723928 | 0.77 | CNR2 (0.40) | CNR2CNR1ALDH1A1NPC1RAB9A | |
| SCHEMBL14724233 | 0.77 | CNR1 (0.40) | CNR2CNR1ALDH1A1EGFRGAA | |
| SCHEMBL9892807 | 0.77 | CNR2 (0.37) | CNR2CNR1 | |
| SCHEMBL1089518 | 0.77 | TRPM8 (0.38) | CNR2CNR1ALDH1A1EGFRGAA | |
| SCHEMBL23870092 | 0.77 | CYP2C9 (0.35) | ALDH1A1EGFRGAATRPM8MAPT | |
| SCHEMBL427051 | 0.76 | ALDH1A1 (0.43) | ALDH1A1EGFRGAATRPM8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252488-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |
| WO-2021242505-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2021-12-02 | — | — | WO | disclosed |
| US-8383615-B2 | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| WO-2012076673-A1 | 6-AMINO-2-PHENYLAMINO-1H-BENZIMIDAZOLE-5-CARBOXAMIDE- DERIVATIVES AND THEIR USE AS MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |