Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673995 | 1.00 | GRIN2B (0.68) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL9947164 | 0.98 | GRIN2B (0.66) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL7436031 | 0.98 | GRIN2B (0.66) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL9506641 | 0.98 | GRIN2B (0.66) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL9018525 | 0.98 | GRIN2B (0.66) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL7938970 | 0.96 | GRIN2B (0.64) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL9727205 | 0.96 | GRIN2B (0.68) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL12670642 | 0.90 | GRIN2B (0.65) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL13468211 | 0.88 | GRIN2B (0.62) | GRIN2BHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL4486847 | 0.87 | CHRNA7 (0.59) | GRIN2BHTR1AHTR7OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | GRIN2B 183/4885HTR1A 13/4885HTR7 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.