Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998153 | 0.89 | THRA (0.47) | THRARARBMAPTL3MBTL1GAA | |
| SCHEMBL9808683 | 0.88 | MAPT (0.47) | THRARARBMAPTL3MBTL1PARP10 | |
| SCHEMBL19077766 | 0.86 | APP (0.47) | THRARARBMAPTL3MBTL1PARP10 | |
| SCHEMBL17921588 | 0.86 | APP (0.47) | THRARARBMAPTL3MBTL1PARP10 | |
| SCHEMBL316964 | 0.86 | APP (0.47) | THRARARBMAPTL3MBTL1PARP10 | |
| SCHEMBL17921585 | 0.86 | MAPT (0.50) | THRARARBMAPTL3MBTL1PARP10 | |
| SCHEMBL19077767 | 0.86 | APP (0.47) | THRARARBMAPTL3MBTL1PARP10 | |
| SCHEMBL16139896 | 0.86 | APP (0.47) | THRARARBMAPTL3MBTL1PARP10 | |
| SCHEMBL402554 | 0.85 | L3MBTL1 (0.58) | MAPTL3MBTL1GAALMNATP53 | |
| SCHEMBL10713224 | 0.85 | TP53 (0.58) | RARBL3MBTL1GAATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10451966-B2 | — | — | 2019-10-22 | — | — | US | disclosed |
| US-20120147323-A1 | OPHTHALMIC LENSES MODIFIED WITH FUNCTIONAL GROUPS AND METHODS OF MAKING THEREOF | ALCON INC. (CH) | 2012-06-14 | — | — | US | disclosed |