Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 6/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536515 | 0.97 | ADRA1B (0.40) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL9947439 | 0.97 | ADRA1B (0.40) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL9947442 | 0.95 | HRH3 (0.40) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL9947441 | 0.95 | HRH3 (0.40) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL9947446 | 0.95 | ACHE (0.39) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL9947453 | 0.95 | KMT2A (0.42) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL9947455 | 0.93 | HRH3 (0.41) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL9947468 | 0.93 | HRH3 (0.41) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL9947466 | 0.93 | HRH3 (0.41) | ADRA1BADRA1APOLBKMT2AMEN1 | |
| SCHEMBL8590432 | 0.92 | KMT2A (0.40) | ADRA1BADRA1APOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9993559-B2 | N-alkyl lactam ethers, and compositions and uses thereof | ISP INVESTMENTS LLC (US) | 2018-06-12 | — | — | US | disclosed |
| US-20160271254-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160271254-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-9351484-B2 | N-alkyl lactam ethers, and compositions and uses thereof | ISP INVESTMENTS INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-9351484-B2 | N-alkyl lactam ethers, and compositions and uses thereof | ISP INVESTMENTS INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140045698-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-20140045698-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-20120148514-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120148514-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271254-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | USP8, MLST8, CYP2C8 | ADRA1B 4020/4885ADRA1A 3119/4885POLB 1260/4885 |
| US-20140045698-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | USP8, MLST8, CYP2C8 | ADRA1B 4020/4885ADRA1A 3119/4885POLB 1260/4885 |
| US-20120148514-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | USP8, MLST8, CYP2C8 | ADRA1B 4020/4885ADRA1A 3119/4885POLB 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.