Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 14/20 | 0.36 |
| ▸ | CDK9 | P50750 | 14/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9947615 | 0.98 | CCNT1 (0.36) | CCNT1CDK9PTGDRSYKENPP2 | |
| SCHEMBL982441 | 0.96 | CCNT1 (0.37) | CCNT1CDK9PTGDRSYKENPP2 | |
| SCHEMBL979615 | 0.86 | CCNT1 (0.38) | CCNT1CDK9PTGDRSYKTDO2 | |
| SCHEMBL980834 | 0.82 | CCNT1 (0.37) | CCNT1CDK9PTGDRENPP2TDO2 | |
| SCHEMBL978848 | 0.82 | CCNT1 (0.42) | CCNT1CDK9PTGDRSYKTDO2 | |
| SCHEMBL979909 | 0.80 | CCNT1 (0.37) | CCNT1CDK9PTGDRENPP2TDO2 | |
| SCHEMBL1052390 | 0.72 | ADORA3 (0.44) | CCNT1CDK9SYKTDO2 | |
| SCHEMBL980281 | 0.72 | TDP1 (0.48) | CCNT1CDK9SYKTDO2 | |
| SCHEMBL980915 | 0.71 | CCNT1 (0.48) | CCNT1CDK9 | |
| SCHEMBL981820 | 0.70 | PTGDR (0.39) | CCNT1CDK9PTGDRSYKENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207344-B2 | GPR119 agonists | ELI LILLY AND COMPANY (US) | 2012-06-26 | — | — | US | disclosed |