SCHEMBL979909

SCHEMBL979909

CC(C)(F)CC(Oc1ccc(C2=CCN(S(C)(=O)=O)CC2)cc1)C1CCNCC1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 15/20 0.37
CDK9 P50750 15/20 0.37
PTGDR Q13258 1/20 0.37
ENPP2 Q13822 1/20 0.36
TDO2 P48775 1/20 0.35
LMNA P02545 1/20 0.34
THRB P10828 1/20 0.34
HTR1D P28221 1/20 0.34
HTR1B P28222 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980834 0.94 CCNT1 (0.37) CCNT1CDK9PTGDRENPP2TDO2
SCHEMBL980915 0.88 CCNT1 (0.48) CCNT1CDK9
SCHEMBL978848 0.83 CCNT1 (0.42) CCNT1CDK9PTGDRTDO2LMNA
SCHEMBL982441 0.81 CCNT1 (0.37) CCNT1CDK9PTGDRENPP2TDO2
SCHEMBL9947643 0.80 CCNT1 (0.36) CCNT1CDK9PTGDRENPP2TDO2
SCHEMBL9947615 0.80 CCNT1 (0.36) CCNT1CDK9PTGDRENPP2TDO2
SCHEMBL979615 0.79 CCNT1 (0.38) CCNT1CDK9PTGDRTDO2LMNA
SCHEMBL981820 0.77 PTGDR (0.39) CCNT1CDK9PTGDRENPP2TDO2
SCHEMBL1052390 0.75 ADORA3 (0.44) CCNT1CDK9TDO2
SCHEMBL980281 0.75 TDP1 (0.48) CCNT1CDK9TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207344-B2 GPR119 agonists ELI LILLY AND COMPANY (US) 2012-06-26 US disclosed
EP-2454251-A1 GPR119 AGONISTS Eli Lilly and Company (US) 2012-05-23 EP disclosed
WO-2011008663-A1 GPR119 AGONISTS ELI LILLY AND COMPANY (US) 2011-01-20 WO disclosed
US-20110015199-A1 GPR119 Agonists ELI LILLY AND COMPANY (US) 2011-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015199-A1 GPR119 Agonists GPR119, GLP1R, GCGR CCNT1 4475/4885CDK9 2128/4885PTGDR 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.