⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948039 | 0.92 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL9948422 | 0.87 | — | — | |
| SCHEMBL9948424 | 0.87 | — | — | |
| SCHEMBL9947895 | 0.86 | APLNR (0.36) | — | |
| SCHEMBL9948193 | 0.86 | — | — | |
| SCHEMBL15435592 | 0.84 | — | — | |
| SCHEMBL9948207 | 0.83 | DPP4 (0.34) | — | |
| SCHEMBL9948382 | 0.83 | AGTR1 (0.30) | — | |
| SCHEMBL9948341 | 0.81 | APLNR (0.33) | — | |
| SCHEMBL9948451 | 0.81 | APLNR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315493-B2 | Phenylpyridine derivative and drug containing same | KOWA COMPANY, LTD. (JP) | 2016-04-19 | — | — | US | disclosed |
| CN-102639527-B | Novel phenylpyridine derivative and medicinal agent comprising same | KOWA CO | 2014-11-05 | — | — | CN | disclosed |
| US-8778954-B2 | Phenylpyridine derivative and medicinal agent comprising same | KOWA COMPANY, LTD. (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20140011823-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND DRUG CONTAINING SAME | KOWA COMPANY, LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
| CN-103459380-A | Novel phenylpyridine derivative and medicine containing the same | KOWA CO | 2013-12-18 | — | — | CN | disclosed |
| US-20120165353-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME | KOWA COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |