Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 4/20 | 0.47 |
| ▸ | SHBG | P04278 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643602 | 0.83 | SHBG (0.35) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL3356884 | 0.80 | CYP19A1 (0.44) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL14099186 | 0.78 | ALDH1A1 (0.75) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL25863847 | 0.78 | ALDH1A1 (0.75) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL12884330 | 0.78 | ALDH1A1 (0.75) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL25863884 | 0.78 | ALDH1A1 (0.75) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL3225293 | 0.76 | SHBG (0.65) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL5550822 | 0.76 | SHBG (0.65) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL11515579 | 0.76 | SHBG (0.68) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL3816340 | 0.76 | SHBG (0.68) | SERPINA6SHBGALDH1A1SLC22A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207150-B2 | 17β-cyano-19-nor-androst-4-ene derivative, its use and medicaments comprising the derivative | Bayer Pharma AG (DE) | 2012-06-26 | — | — | US | disclosed |