Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165134 | 0.83 | CA12 (0.46) | CA12CA9CA1CA3CA4 | |
| SCHEMBL28067946 | 0.82 | CA12 (0.53) | CA12CA9CA1CA3CA4 | |
| SCHEMBL6123011 | 0.80 | APP (0.48) | PDE3BPDE3AELANEKDM4EALDH1A1 | |
| SCHEMBL4553044 | 0.70 | AR (0.51) | CA12CA9CA1CA3CA4 | |
| SCHEMBL6122691 | 0.69 | CA12 (0.51) | CA12CA9CA1CA3CA4 | |
| SCHEMBL4282528 | 0.69 | AR (0.59) | CA12CA9CA1CA3CA4 | |
| Methyl Alcohol SCHEMBL10568722 | 0.68 | CA12 (0.87) | CA12CA9CA1CA3CA4 | |
| SCHEMBL29379051 | 0.68 | AR (0.65) | TNKS2CYP1A2CYP2C19PDE3BPDE3A | |
| SCHEMBL74712 | 0.68 | AR (0.65) | TNKS2CYP1A2CYP2C19PDE3BPDE3A | |
| SCHEMBL8621 | 0.67 | CA12 (1.00) | CA12CA9CA1CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006510-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2011-01-20 | — | — | WO | claimed |
| WO-2011006510-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2011-01-20 | — | — | WO | disclosed |