SCHEMBL28067946

SCHEMBL28067946

Cc1cc(=O)[nH]c2cc(N(C)C)ccc12.O=c1ccc2ccccc2[nH]1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.53
CA9 Q16790 2/20 0.53
CA1 P00915 1/20 0.53
CA3 P07451 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA13 Q8N1Q1 1/20 0.53
CA14 Q9ULX7 1/20 0.53
CA5B Q9Y2D0 1/20 0.53
TNKS2 Q9H2K2 7/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 1/20 0.53
AR P10275 3/20 0.51
KDM4E B2RXH2 3/20 0.46
GLA P06280 2/20 0.46
GAA P10253 2/20 0.46
TP53 P04637 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74712 0.86 AR (0.65) TNKS2CYP1A2CYP2C19ARKDM4E
SCHEMBL29379051 0.86 AR (0.65) TNKS2CYP1A2CYP2C19ARKDM4E
SCHEMBL994883 0.82 CA12 (0.44) CA12CA9CA1CA3CA4
SCHEMBL28165134 0.81 CA12 (0.46) CA12CA9CA1CA3CA4
SCHEMBL4553044 0.80 AR (0.51) CA12CA9CA1CA3CA4
SCHEMBL4282528 0.75 AR (0.59) CA12CA9CA1CA3CA4
SCHEMBL29351086 0.72 CA12 (1.00) CA12CA9CA1CA3CA4
SCHEMBL8621 0.72 CA12 (1.00) CA12CA9CA1CA3CA4
SCHEMBL5437282 0.72 CA12 (1.00) CA12CA9CA1CA3CA4
SCHEMBL30958273 0.72 CA12 (1.00) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103443201-B The polycarbonate-polysiloxane compound that the thermotolerance improved is transparent SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2016-06-01 CN disclosed