SCHEMBL9948878

SCHEMBL9948878

CC[C@@H](Oc1cccc(CNCC(Oc2ccccc2)c2nc3cc(F)ccc3o2)c1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.56
PPARA Q07869 20/20 0.56
PPARG P37231 15/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511703 0.93 PPARA (0.57) PPARDPPARAPPARG
SCHEMBL1011033 0.91 PPARA (0.53) PPARDPPARAPPARG
SCHEMBL1010183 0.86 PPARD (0.54) PPARDPPARAPPARG
SCHEMBL1010591 0.86 PPARA (0.49) PPARDPPARAPPARG
SCHEMBL1012218 0.85 PPARA (0.56) PPARDPPARAPPARG
SCHEMBL1008833 0.82 PPARA (0.52) PPARDPPARAPPARG
SCHEMBL1009736 0.82 PPARA (0.55) PPARDPPARAPPARG
SCHEMBL1009258 0.82 PPARA (0.48) PPARDPPARAPPARG
SCHEMBL1012230 0.82 PPARD (0.45) PPARDPPARAPPARG
SCHEMBL1010688 0.80 PPARD (0.52) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484361-B1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO (JP) 2015-11-11 EP claimed
US-20120165377-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2012-06-28 US claimed
US-20230321051-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2023-10-12 US disclosed
US-20230019803-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2023-01-19 US disclosed
US-20210205274-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2021-07-08 US disclosed
US-20200246315-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2020-08-06 US disclosed
US-20200030299-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2020-01-30 US disclosed
US-20190167644-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO. LTD. (JP) 2019-06-06 US disclosed
US-20180078530-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2018-03-22 US disclosed
US-20160243086-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2016-08-25 US disclosed
EP-2484361-B1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO (JP) 2015-11-11 EP disclosed
EP-2484361-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT Kowa Company, Ltd. (JP) 2012-08-08 EP disclosed
US-20120165377-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT KOWA CO., LTD. (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210205274-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, FGFR1 PPARD 67/4885PPARA 20/4885PPARG 32/4885
US-20200030299-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, FGFR1 PPARD 67/4885PPARA 20/4885PPARG 32/4885
US-20180078530-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, FGFR1 PPARD 67/4885PPARA 20/4885PPARG 32/4885
US-20230321051-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, FGFR1 PPARD 68/4885PPARA 22/4885PPARG 35/4885
US-20230019803-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, FGFR1 PPARD 67/4885PPARA 20/4885PPARG 32/4885
US-20190167644-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, CPT1B PPARD 66/4885PPARA 21/4885PPARG 33/4885
US-20160243086-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, FGFR1 PPARD 67/4885PPARA 20/4885PPARG 32/4885
US-20120165377-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, FGFR1 PPARD 67/4885PPARA 20/4885PPARG 32/4885
US-20200246315-A1 AGENT FOR REDUCING VISCERAL FAT WEIGHT FABP4, FGF1, FGFR1 PPARD 64/4885PPARA 21/4885PPARG 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.