Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508414 | 0.89 | TDP1 (0.42) | TDP1ATMNPSR1NAMPTALDH1A1 | |
| SCHEMBL9949532 | 0.85 | TDP1 (0.44) | TDP1ATMNPSR1NAMPTALDH1A1 | |
| SCHEMBL190944 | 0.84 | TDP1 (0.45) | TDP1ATMNPSR1NAMPTALDH1A1 | |
| SCHEMBL29405225 | 0.84 | TDP1 (0.45) | TDP1ATMNPSR1NAMPTALDH1A1 | |
| SCHEMBL5851967 | 0.82 | LMNA (0.37) | ALDH1A1KDM4EHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL29885636 | 0.81 | INPPL1 (0.52) | TDP1ATMNPSR1NAMPTALDH1A1 | |
| SCHEMBL29258964 | 0.81 | TDP1 (0.42) | TDP1ATMNPSR1NAMPTALDH1A1 | |
| SCHEMBL29462669 | 0.81 | TDP1 (0.46) | TDP1ATMNPSR1NAMPTALDH1A1 | |
| SCHEMBL284461 | 0.81 | INPPL1 (0.52) | TDP1ATMNPSR1NAMPTALDH1A1 | |
| SCHEMBL818786 | 0.81 | TDP1 (0.46) | TDP1ATMNPSR1NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410203-B2 | Phosphorus compound, method of preparing the same and flame retardant thermoplastic resin composition including the same | CHEIL INDUSTRIES INC. (KR) | 2013-04-02 | — | — | US | disclosed |
| US-20120165444-A1 | Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same | CHEIL INDUSTRIES INC. (KR) | 2012-06-28 | — | — | US | disclosed |
| EP-2468814-A1 | Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same | Cheil Industries Inc. (KR) | 2012-06-27 | — | — | EP | disclosed |
| US-4918056-A | ANTITUMOR AGENTS | HEALTH RESEARCH, INC. (ROSWELL PARK DIVISION) (US) | 1990-04-17 | — | — | US | disclosed |
| US-4622392-A | ANTICARCINOGENIC AGENTS | HEALTH RESEARCH INC. (ROSWELL PARK DIVISION) (US) | 1986-11-11 | — | — | US | disclosed |
| US-4291024-A | ANTICANCER AGENTS | UNIVERSITY OF RHODE ISLAND | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165444-A1 | Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same | RPP30, RER1, TAF11 | TDP1 1726/4885ATM 2954/4885NPSR1 1981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.