SCHEMBL9949291

SCHEMBL9949291

COC(=O)CN(CC(=O)O)c1ccc(N(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.47
HPGD P15428 7/20 0.47
RAB9A P51151 6/20 0.44
NPC1 O15118 5/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
NOX1 Q9Y5S8 2/20 0.44
TP53 P04637 1/20 0.44
ESR2 Q92731 1/20 0.44
ALDH1A1 P00352 8/20 0.42
KDM4E B2RXH2 3/20 0.42
MEN1 O00255 1/20 0.42
THRB P10828 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GAA P10253 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPK1 P28482 3/20 0.41
HSD17B10 Q99714 2/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13644976 0.88 ALDH1A1 (0.50) MAPTHPGDRAB9ANPC1SMN1; SMN2
SCHEMBL13603850 0.87 ALDH1A1 (0.40) MAPTRAB9AALDH1A1GAA
SCHEMBL13680117 0.87 KEAP1 (0.46) MAPTRAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL3841166 0.86 TDP1 (0.44) RAB9ANPC1SMN1; SMN2NOX1ALDH1A1
SCHEMBL13645020 0.85 ALDH1A1 (0.43) MAPTRAB9ATP53ALDH1A1KDM4E
SCHEMBL13603843 0.85 ALDH1A1 (0.42) MAPTRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL13603842 0.85 KEAP1 (0.52) MAPTRAB9ANPC1SMN1; SMN2NOX1
SCHEMBL13611307 0.84 CYP4F2 (0.39) MAPTRAB9AALDH1A1KDM4E
SCHEMBL13603864 0.84 MAPT (0.48) MAPTHPGDRAB9ANPC1SMN1; SMN2
SCHEMBL13603857 0.84 ALDH1A1 (0.41) MAPTRAB9ANPC1SMN1; SMN2NOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2471655-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2016-08-17 EP disclosed
CN-102529310-B Original edition of lithographic printing plate and lithographic process FUJI FILM CORP. (JP) 2015-09-16 CN disclosed
CN-102653158-B Lithographic printing plate precursor and plate making method thereof FUJIFILM CORP 2015-04-15 CN disclosed
US-8435720-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2013-05-07 US disclosed
CN-102653158-A Lithographic printing plate precursor and plate making method thereof FUJIFILM CORP 2012-09-05 CN disclosed
US-20120219911-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF FUJIFILM CORPORATION (JP) 2012-08-30 US disclosed
EP-2492751-A1 Lithographic printing plate precursor and plate making method thereof Fujifilm Corporation (JP) 2012-08-29 EP disclosed
CN-102529310-A Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP 2012-07-04 CN disclosed
US-20120160118-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2012-06-28 US disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 US disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-7582410-B2 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-7582410-B2 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-7416835-B2 Polymerizable composition FUJIFILM CORPORATION (JP) 2008-08-26 US disclosed
US-7416835-B2 Polymerizable composition FUJIFILM CORPORATION (JP) 2008-08-26 US disclosed
US-20080038663-A1 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed
US-20080038663-A1 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed