Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18795997 | 0.76 | CYP1A2 (0.44) | CYP1A2PDGFRBPDGFRAHPGDHTT | |
| SCHEMBL28028241 | 0.74 | CYP1A2 (0.48) | SLC22A12CYP1A2PDGFRBPDGFRAHPGD | |
| SCHEMBL29105728 | 0.73 | HPGD (0.56) | CYP1A2PDGFRBPDGFRAHPGDHTT | |
| SCHEMBL30618060 | 0.73 | HPGD (0.56) | CYP1A2PDGFRBPDGFRAHPGDHTT | |
| SCHEMBL6393371 | 0.72 | PRKD3 (0.48) | HTR2CHTR6PDGFRBPDGFRAPTPN11 | |
| Benzene SCHEMBL28157980 | 0.72 | CYP1A2 (0.47) | SLC22A12CYP1A2PDGFRBPDGFRAHPGD | |
| SCHEMBL29484715 | 0.72 | NOTUM (0.45) | HTR2CHTR6PTPN11ALDH1A1PGR | |
| SCHEMBL8863558 | 0.72 | NOTUM (0.45) | HTR2CHTR6PTPN11ALDH1A1PGR | |
| SCHEMBL18796454 | 0.71 | ALDH1A1 (0.55) | HPGDHTTALDH1A1 | |
| SCHEMBL28061034 | 0.71 | PDGFRB (0.58) | CYP1A2PDGFRBPDGFRAALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288410-B2 | 3-substituted quinolinium and 7H-indolo[2,3-c]quinolinium salts as new antiinfectives | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 2012-10-16 | — | — | US | disclosed |
| US-8288410-B2 | 3-substituted quinolinium and 7H-indolo[2,3-c]quinolinium salts as new antiinfectives | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 2012-10-16 | — | — | US | disclosed |
| US-8288410-B2 | 3-substituted quinolinium and 7H-indolo[2,3-c]quinolinium salts as new antiinfectives | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 2012-10-16 | — | — | US | disclosed |
| US-20120165369-A1 | 3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
| US-20120165369-A1 | 3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
| US-20120165369-A1 | 3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165369-A1 | 3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES | IDO1, IDO2, NQO2 | SLC22A12 2404/4885ULK1 2015/4885HTR2C 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.