Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29105728 | 0.77 | HPGD (0.56) | CYP1A2BIRC5PDGFRBPDGFRAHPGD | |
| SCHEMBL30618060 | 0.77 | HPGD (0.56) | CYP1A2BIRC5PDGFRBPDGFRAHPGD | |
| SCHEMBL9949544 | 0.76 | SLC22A12 (0.47) | CYP1A2PDGFRBPDGFRAHPGDHTT | |
| SCHEMBL18796454 | 0.74 | ALDH1A1 (0.55) | HPGDHTTALDH1A1MEN1KMT2A | |
| SCHEMBL8094448 | 0.74 | CYP1A2 (0.57) | CYP1A2BIRC5PDGFRBPDGFRAHPGD | |
| SCHEMBL20591235 | 0.71 | NPC1 (0.61) | CYP1A2PDGFRBPDGFRAHPGDHTT | |
| SCHEMBL28061034 | 0.71 | PDGFRB (0.58) | CYP1A2PDGFRBPDGFRAALDH1A1SMN1; SMN2 | |
| SCHEMBL24593163 | 0.71 | CYP1A2 (0.53) | CYP1A2BIRC5PDGFRBPDGFRAHPGD | |
| SCHEMBL271506 | 0.71 | CYP1A2 (0.59) | CYP1A2BIRC5PDGFRBPDGFRAHPGD | |
| SCHEMBL271505 | 0.71 | CYP1A2 (0.53) | CYP1A2BIRC5PDGFRBPDGFRAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | claimed |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | claimed |
| EP-3368514-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | claimed |
| CN-108349897-A | Trisubstituted silylphenoxyheterocycles and analogs | 拜耳作物科学股份公司 | 2018-07-31 | — | — | CN | claimed |
| WO-2017072283-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | claimed |
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-16 | — | — | US | disclosed |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | disclosed |
| EP-3368514-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| CN-108349897-A | Trisubstituted silylphenoxyheterocycles and analogs | 拜耳作物科学股份公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017072283-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | PIK3C3, ERG28, DDT | CYP1A2 58/4885BIRC5 826/4885PDGFRB 4258/4885 |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | PIK3C3, ERG28, DDT | CYP1A2 58/4885BIRC5 826/4885PDGFRB 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.