SCHEMBL994960

SCHEMBL994960

COc1ccc(/C=N/c2ccc(C)cc2)c(O)c1

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 6/20 0.66
▸ MAPT P10636 3/20 0.64
▸ ALDH1A1 P00352 2/20 0.64
▸ GAA P10253 1/20 0.64
▸ MEN1 O00255 1/20 0.62
▸ KMT2A Q03164 1/20 0.62
▸ HSD17B10 Q99714 1/20 0.62
▸ KDM4E B2RXH2 1/20 0.58
▸ LMNA P02545 1/20 0.57
▸ CA1 P00915 3/20 0.56
▸ CA2 P00918 3/20 0.56
▸ TRIM24 O15164 1/20 0.53
▸ TYR P14679 1/20 0.53
▸ TRIM33 Q9UPN9 1/20 0.53
▸ S100B P04271 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL994961 1.00 MAOB (0.66) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL992774 0.88 CA1 (0.71) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL992775 0.88 CA1 (0.71) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL10719675 0.87 MAOB (0.64) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL10567450 0.86 MAPT (0.72) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL10567452 0.86 MAPT (0.72) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL13385757 0.84 MAOB (0.62) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL13385780 0.84 MAOB (0.62) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL13385758 0.84 MAOB (0.62) MAOBMAPTALDH1A1GAAMEN1
SCHEMBL18763297 0.84 MAPT (0.67) MAOBMAPTALDH1A1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8519069-B2 Catalytic complex for olefin metathesis reactions, process for the preparation thereof and use thereof RIMTEC CORPORATION (JP) 2013-08-27 — — US disclosed
EP-2280017-B1 Catalytic complex for olefin metathesis reactions, process for the preparation thereof and use thereof RIMTEC CORP (JP) 2013-01-02 — — EP disclosed
US-20120271019-A1 CATALYTIC COMPLEX FOR OLEFIN METATHESIS REACTIONS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF TELENE S.A.S. (FR) 2012-10-25 — — US disclosed
EP-2280017-A1 Catalytic complex for olefin metathesis reactions, process for the preparation thereof and use thereof Telene SAS (FR) 2011-02-02 — — EP disclosed
WO-2011009721-A1 CATALYTIC COMPLEX FOR OLEFIN METATHESIS REACTIONS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF TELENE S.A.S. (FR) 2011-01-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120271019-A1 CATALYTIC COMPLEX FOR OLEFIN METATHESIS REACTIONS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF COASY, POR, DHPS MAOB 48/4885MAPT 3177/4885ALDH1A1 1784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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