Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 5/20 | 0.64 |
| ▸ | S100B | P04271 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567450 | 1.00 | MAPT (0.72) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL994960 | 0.86 | MAOB (0.66) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL994961 | 0.86 | MAOB (0.66) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL10719675 | 0.85 | MAOB (0.64) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL11404194 | 0.85 | MAPT (0.64) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL11404191 | 0.85 | MAPT (0.64) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL10564981 | 0.84 | MAPT (1.00) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL10564983 | 0.84 | MAPT (1.00) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL13385757 | 0.82 | MAOB (0.62) | MAPTHSD17B10MEN1KMT2AGAA | |
| SCHEMBL13385780 | 0.82 | MAOB (0.62) | MAPTHSD17B10MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4828568-A | N-(2,4-DIHYDROXYBENZYLIDENE)AMINO COMPOUNDS AS PRIMARY COUPLERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-05-09 | — | — | US | claimed |
| US-11166891-B2 | Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-11-09 | — | — | US | disclosed |
| US-20200078279-A1 | BIS PHENYL HEXA TRIEN DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR SKIN WHITENING CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KP) | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166891-B2 | Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient | TYR, MITF, TPH1 | MAPT 603/4885HSD17B10 2708/4885MEN1 4248/4885 |
| US-20200078279-A1 | BIS PHENYL HEXA TRIEN DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR SKIN WHITENING CONTAINING THE SAME AS AN ACTIVE INGREDIENT | TYR, MITF, TPH1 | MAPT 603/4885HSD17B10 2708/4885MEN1 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.