Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061139 | 0.82 | MAPT (0.41) | KDM4E | |
| SCHEMBL982385 | 0.68 | — | — | |
| SCHEMBL4491679 | 0.64 | — | — | |
| SCHEMBL11005327 | 0.62 | — | — | |
| SCHEMBL31099215 | 0.61 | TRIM58 (0.30) | — | |
| SCHEMBL19020845 | 0.57 | GPR3 (0.68) | KDM4EGPR3 | |
| SCHEMBL16535871 | 0.55 | GPR3 (0.52) | KDM4EGPR3 | |
| SCHEMBL1143155 | 0.55 | KDM4E (0.42) | KDM4EGPR3 | |
| SCHEMBL29412402 | 0.55 | KDM4E (0.42) | KDM4EGPR3 | |
| SCHEMBL28551604 | 0.55 | GPR3 (0.42) | KDM4EGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288410-B2 | 3-substituted quinolinium and 7H-indolo[2,3-c]quinolinium salts as new antiinfectives | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 2012-10-16 | — | — | US | disclosed |
| US-20120165369-A1 | 3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165369-A1 | 3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES | IDO1, IDO2, NQO2 | KDM4E 1592/4885GPR3 1107/4885LRRK2 1220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.