Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM33 | Q9BZ11 | 8/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 11/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996102 | 1.00 | ADAM33 (0.45) | ADAM33ADAM17MMP1MMP3ALDH1A1 | |
| SCHEMBL2681236 | 0.87 | ADAM33 (0.54) | ADAM33ADAM17MMP1MMP3ALDH1A1 | |
| SCHEMBL2681241 | 0.87 | ADAM33 (0.54) | ADAM33ADAM17MMP1MMP3ALDH1A1 | |
| SCHEMBL14245119 | 0.87 | ADAM17 (0.57) | ADAM33ADAM17MMP1MMP3ALDH1A1 | |
| SCHEMBL14245537 | 0.87 | ADAM17 (0.57) | ADAM33ADAM17MMP1MMP3ALDH1A1 | |
| SCHEMBL27853836 | 0.86 | ADAM17 (0.56) | ADAM33ADAM17MMP1MMP3ALDH1A1 | |
| SCHEMBL2680366 | 0.85 | ADAM33 (0.56) | ADAM33MMP3ALDH1A1 | |
| SCHEMBL2680361 | 0.85 | ADAM33 (0.56) | ADAM33MMP3ALDH1A1 | |
| SCHEMBL995056 | 0.78 | ADAM17 (0.74) | ADAM33ADAM17MMP1MMP3ADAM9 | |
| SCHEMBL997188 | 0.77 | ADAM17 (0.55) | ADAM33ADAM17MMP1MMP3ADAM9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2801568-A1 | Benzene-sulphonamide compounds, method for synthesising and use in medicine and in cosmetics | Galderma Research & Development (FR) | 2014-11-12 | — | — | EP | disclosed |
| EP-2448920-B1 | Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine | GALDERMA RES & DEV (FR) | 2014-08-13 | — | — | EP | disclosed |
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |