Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.84 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.84 |
| ▸ | TSHR | P16473 | 4/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215174 | 0.92 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL39447 | 0.92 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL15476044 | 0.92 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL9950267 | 0.90 | ALDH1A1 (0.84) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL1417898 | 0.88 | ALDH1A1 (0.61) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL6328763 | 0.87 | ALDH1A1 (0.90) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL29251251 | 0.87 | ALDH1A1 (0.90) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL20996740 | 0.85 | ALDH1A1 (0.87) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL18973334 | 0.84 | ALDH1A1 (0.85) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 | |
| SCHEMBL9933293 | 0.84 | ALDH1A1 (0.85) | ALDH1A1HSD17B10ALOX15ALOX12CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566828-B2 | Composition based on natural rubber and a polyimine compound | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2017-02-14 | — | — | US | disclosed |
| EP-2451656-B1 | composition based on natural rubber and a polyimine compound | MICHELIN & CIE (FR) | 2015-11-25 | — | — | EP | disclosed |
| US-20120165449-A1 | COMPOSITION BASED ON NATURAL RUBBER AND A POLYIMINE COMPOUND | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2012-06-28 | — | — | US | disclosed |