SCHEMBL9950467

SCHEMBL9950467

CCC1(COCc2ccc(-c3ccc(COCC4(C)COC4)cc3)cc2)COC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
GPR84 Q9NQS5 1/20 0.31
EPHX1 P07099 1/20 0.31
ACACB O00763 1/20 0.31
PTGES O14684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13320413 0.96 TSHR (0.34) TSHRGPR84EPHX1ACACB
SCHEMBL686052 0.93 TSHR (0.36) TSHRPTGES
SCHEMBL9936046 0.89 ACACB (0.34) TSHRGPR84EPHX1ACACBPTGES
SCHEMBL9950073 0.89 GPR84 (0.30) GPR84
SCHEMBL17857761 0.88 ACACB (0.34) TSHRGPR84EPHX1ACACB
SCHEMBL36601 0.88 TSHR (0.38) TSHR
SCHEMBL2035091 0.87 IDO1 (0.41) TSHR
SCHEMBL3161401 0.86 TSHR (0.37) TSHR
SCHEMBL13721129 0.86 TSHR (0.37) TSHR
SCHEMBL23169777 0.86 TSHR (0.33) TSHRPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722769-B2 Light-curing resin composition and optical material NITTO DENKO CORPORATION (JP) 2014-05-13 US disclosed
US-20120165424-A1 LIGHT-CURING RESIN COMPOSITION AND OPTICAL MATERIAL NITTO DENKO CORPORATION (JP) 2012-06-28 US disclosed
US-8008429-B2 Thermosetting resin composition NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
US-8008429-B2 Thermosetting resin composition NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
US-20100130697-A1 Thermosetting Resin Composition NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2010-05-27 US disclosed
US-20100130697-A1 Thermosetting Resin Composition NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2010-05-27 US disclosed