Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.51 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.51 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.51 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.51 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.51 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.51 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.51 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022804 | 0.92 | CNR1 (0.52) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL10084300 | 0.89 | CNR1 (0.55) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL5023722 | 0.89 | CNR1 (0.55) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL9951729 | 0.87 | HDAC4 (0.64) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL5018302 | 0.85 | BDKRB2 (0.46) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL5018249 | 0.85 | BDKRB2 (0.46) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL1245446 | 0.85 | BDKRB2 (0.46) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL2747835 | 0.85 | CNR1 (0.54) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL4950439 | 0.85 | CNR1 (0.54) | SCN9ACNR1CNR2ADCY6ADCY3 | |
| SCHEMBL2748147 | 0.84 | HDAC4 (0.57) | SCN9ACNR1CNR2ADCY6ADCY3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268865-B2 | Quaternary alkyl ammonium bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20120165276-A1 | QUATERNARY ALKYL AMMONIUM BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165276-A1 | QUATERNARY ALKYL AMMONIUM BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCC1, SLC47A1 | SCN9A 972/4885CNR1 3822/4885CNR2 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.