Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14779262 | 0.80 | GAA (0.46) | ALDH1A1GAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL890842 | 0.79 | GAA (0.45) | ALDH1A1GAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8345094 | 0.79 | GAA (0.45) | AGERALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL3838479 | 0.77 | CA2 (0.44) | ALDH1A1MAPTGAACYP3A4CYP2C9 | |
| SCHEMBL7924128 | 0.77 | AGER (0.44) | AGERALDH1A1MAPTMCOLN3GAA | |
| SCHEMBL766861 | 0.77 | CA2 (0.44) | ALDH1A1MAPTGAACYP3A4CYP2C9 | |
| SCHEMBL92244 | 0.77 | CA2 (0.44) | ALDH1A1MAPTGAACYP3A4CYP2C9 | |
| SCHEMBL1367273 | 0.76 | AGER (0.43) | AGERALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL9839980 | 0.76 | GAA (0.42) | ALDH1A1GAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5468126 | 0.76 | GAA (0.42) | AGERALDH1A1GAACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008543-A2 | PAN-ANTAGONISTS FOR THE ANDROGEN RECEPTOR AND ANDROGEN RECEPTOR MUTANTS ASSOCIATED WITH ANTI-ANDROGEN WITHDRAWAL | UNIVERSITY OF DELAWARE (US) | 2011-01-20 | — | — | WO | disclosed |