Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199124 | 0.90 | NPC1 (0.68) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL3199664 | 0.87 | MAPT (0.67) | GAANPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL16724721 | 0.85 | GAA (0.64) | GAANPC1RAB9AMEN1KMT2A | |
| SCHEMBL12900992 | 0.82 | NPC1 (0.65) | GAANPC1RAB9AMEN1KMT2A | |
| SCHEMBL10661831 | 0.81 | LMNA (0.68) | GAANPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL9717417 | 0.80 | ITGB3 (0.65) | GAANPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL27273483 | 0.80 | LMNA (0.71) | GAANPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL18030725 | 0.79 | NPC1 (0.54) | GAANPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL27823613 | 0.79 | GAA (0.67) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL1285808 | 0.78 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | GAA 40/4885NPC1 3438/4885RAB9A 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.