SCHEMBL9951577

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10200355	0.83	TRPV3 (0.46)	GCGRTRPV3PSEN1PSEN2APH1B
	SCHEMBL9951000	0.83	GCGR (0.46)	GCGRTRPV3PSEN1PSEN2APH1B
	Hydrochloric Acid SCHEMBL9951424	0.82	GCGR (0.45)	GCGRTRPV3PSEN1PSEN2APH1B
	SCHEMBL2271567	0.82	PSEN1 (0.55)	GCGRPSEN1PSEN2APH1BNCSTN
	SCHEMBL2271563	0.82	PSEN1 (0.55)	GCGRPSEN1PSEN2APH1BNCSTN
	SCHEMBL2271560	0.82	PSEN1 (0.55)	GCGRPSEN1PSEN2APH1BNCSTN
	SCHEMBL2272078	0.80	RARB (0.41)	GCGRTRPV3PSEN1PSEN2APH1B
	SCHEMBL2271994	0.74	PSEN1 (0.48)	GCGRTRPV3PSEN1PSEN2APH1B
	SCHEMBL10200018	0.74	GCGR (0.48)	GCGRTRPV3PSEN1PSEN2APH1B
	SCHEMBL9951087	0.73	TRPV3 (0.45)	TRPV3HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.