Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117867 | 1.00 | OPRK1 (0.36) | OPRK1MAOB | |
| SCHEMBL2118625 | 0.89 | KDM1A (0.33) | OPRK1 | |
| SCHEMBL9950742 | 0.89 | MAOB (0.31) | MAOB | |
| SCHEMBL15162446 | 0.88 | — | — | |
| SCHEMBL9951864 | 0.81 | MAOB (0.32) | MAOB | |
| SCHEMBL2117762 | 0.79 | — | — | |
| SCHEMBL9950857 | 0.79 | — | — | |
| SCHEMBL9951233 | 0.78 | HSD11B1 (0.34) | — | |
| SCHEMBL9950173 | 0.78 | HCRTR2 (0.54) | — | |
| SCHEMBL2119023 | 0.77 | HCRTR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165339-A1 | CYCLOPROPANE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165339-A1 | CYCLOPROPANE DERIVATIVES | HCRTR2, HCRTR1, CNR1 | OPRK1 61/4885MAOB 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.