Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9951951 | 0.95 | REN (0.60) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL9951491 | 0.94 | REN (0.59) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL696345 | 0.91 | REN (0.62) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL9951597 | 0.91 | REN (0.61) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL9952162 | 0.90 | REN (0.72) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL9952151 | 0.90 | REN (0.58) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL9952695 | 0.88 | REN (0.55) | RENCYP3A4KCNH2 | |
| SCHEMBL2792552 | 0.86 | REN (0.63) | RENCYP3A4KCNH2 | |
| SCHEMBL2789976 | 0.86 | REN (0.67) | RENCYP3A4KCNH2 | |
| Hydrochloric Acid SCHEMBL9952035 | 0.86 | REN (0.54) | RENCYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085935-A2 | COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2012-06-28 | — | — | WO | disclosed |