Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952641 | 0.78 | SLC40A1 (0.38) | BRD4SSTR4 | |
| SCHEMBL9953076 | 0.77 | KDM4E (0.33) | KDM4EBRD4COMTEDNRANMT1 | |
| SCHEMBL9953584 | 0.75 | BRD4 (0.40) | BRD4EDNRANMT1HTR2CKMT2A | |
| SCHEMBL9952655 | 0.75 | CNR2 (0.32) | KDM4EBRD4COMTEDNRANMT1 | |
| SCHEMBL9953805 | 0.74 | BRD4 (0.49) | KDM4EHDAC4BRD4COMTEDNRA | |
| SCHEMBL9953585 | 0.67 | ALOX5AP (0.44) | HDAC4BRD4EDNRANMT1HTR2C | |
| SCHEMBL27589731 | 0.65 | BRD4 (0.42) | KDM4EHDAC4BRD4HTR2CCASP1 | |
| SCHEMBL18989038 | 0.65 | MCL1 (0.44) | L3MBTL1 | |
| SCHEMBL29755370 | 0.65 | MCL1 (0.44) | L3MBTL1 | |
| SCHEMBL9953345 | 0.64 | MCL1 (0.34) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |