Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953345 | 0.82 | MCL1 (0.34) | KDM4ENPC1RAB9AALDH1A1DDR1 | |
| SCHEMBL9952807 | 0.81 | HTR2C (0.34) | KDM4ENPC1RAB9ABRD4ALDH1A1 | |
| SCHEMBL9952641 | 0.80 | SLC40A1 (0.38) | BRD4 | |
| SCHEMBL9952655 | 0.77 | CNR2 (0.32) | KDM4EBRD4COMTEDNRANMT1 | |
| SCHEMBL9952073 | 0.77 | KDM4E (0.35) | KDM4EBRD4COMTEDNRANMT1 | |
| SCHEMBL9953584 | 0.73 | BRD4 (0.40) | BRD4EDNRAALDH1A1NMT1HTR2C | |
| SCHEMBL28221677 | 0.72 | PSIP1 (0.39) | HCRTR1HCRTR2ALDH1A1HCAR1DDR1 | |
| SCHEMBL9952788 | 0.72 | HSD11B1 (0.33) | KDM4ENPC1RAB9ABRD4ALDH1A1 | |
| SCHEMBL9953805 | 0.72 | BRD4 (0.49) | KDM4EBRD4COMTHCRTR1HCRTR2 | |
| SCHEMBL18989038 | 0.68 | MCL1 (0.44) | NPC1RAB9AHCRTR1ALDH1A1DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |