Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470039 | 0.89 | CHRM1 (0.38) | TSHRDNM1ALDH1A1LMNACHRM2 | |
| SCHEMBL3185601 | 0.86 | DNM1 (0.34) | TSHRDNM1HPGDALDH1A1HCAR2 | |
| SCHEMBL9871522 | 0.84 | DNM1 (0.38) | TSHRDNM1APEX1THRBHPGD | |
| SCHEMBL11137264 | 0.83 | DNM1 (0.52) | TSHRDNM1APEX1THRBLMNA | |
| SCHEMBL227325 | 0.83 | TSHR (0.57) | TSHRDNM1POLBAPEX1HTT | |
| SCHEMBL1704602 | 0.81 | TSHR (0.66) | TSHRDNM1POLBAPEX1HTT | |
| SCHEMBL8424369 | 0.81 | TSHR (0.66) | TSHRDNM1POLBAPEX1HTT | |
| SCHEMBL16178720 | 0.80 | TSHR (0.41) | TSHRAPEX1TDP1HPGDALDH1A1 | |
| SCHEMBL9640428 | 0.80 | TSHR (0.44) | TSHRDNM1APEX1THRBHCAR2 | |
| SCHEMBL11260774 | 0.80 | TSHR (0.44) | TSHRDNM1APEX1THRBHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654735-B1 | RAPIDLY DISINTEGRATING, SOLID COATED DOSAGE FORM | BASF SE (DE) | 2016-04-13 | — | — | EP | disclosed |
| US-8715729-B2 | Rapidly disintegrating, solid coated dosage form | BASF SE (DE) | 2014-05-06 | — | — | US | disclosed |
| EP-2654735-A2 | RAPIDLY DISINTEGRATING, SOLID COATED DOSAGE FORM | BASF SE (DE) | 2013-10-30 | — | — | EP | disclosed |
| US-20120164223-A1 | RAPIDLY DISINTEGRATING, SOLID COATED DOSAGE FORM | BASF SE (DE) | 2012-06-28 | — | — | US | disclosed |
| WO-2012085043-A2 | RAPIDLY DISINTEGRATING, SOLID COATED DOSAGE FORM | BASF SE (DE) | 2012-06-28 | — | — | WO | disclosed |