Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 19/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955010 | 0.90 | PI4KA (0.59) | PI4KAPIK3CGALDH1A1HPGD | |
| SCHEMBL9954511 | 0.84 | PI4KA (0.64) | PI4KAPIK3CG | |
| SCHEMBL9954271 | 0.81 | PI4KA (0.68) | PI4KAPIK3CG | |
| SCHEMBL9954298 | 0.81 | PI4KA (0.60) | PI4KAPIK3CG | |
| SCHEMBL9954587 | 0.81 | PI4KA (0.61) | PI4KAPIK3CG | |
| SCHEMBL10288670 | 0.80 | PI4KA (0.57) | PI4KAPIK3CGALDH1A1HPGD | |
| SCHEMBL9954452 | 0.79 | PI4KA (0.69) | PI4KAPIK3CG | |
| SCHEMBL10288761 | 0.79 | PI4KA (0.57) | PI4KAPIK3CGALDH1A1HPGD | |
| SCHEMBL9954675 | 0.79 | PI4KA (0.61) | PI4KAPIK3CG | |
| SCHEMBL9954494 | 0.78 | PI4KA (0.63) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |