Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 19/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953192 | 0.83 | PI4KA (0.77) | PI4KAPIK3CG | |
| SCHEMBL9953943 | 0.82 | PI4KA (0.59) | PI4KAPIK3CGPIK3CDPIK3CBPI4KB | |
| SCHEMBL9955010 | 0.81 | PI4KA (0.59) | PI4KAPIK3CG | |
| SCHEMBL9954511 | 0.81 | PI4KA (0.64) | PI4KAPIK3CG | |
| SCHEMBL9953600 | 0.80 | PI4KA (0.57) | PI4KAPIK3CG | |
| SCHEMBL9953490 | 0.80 | PI4KA (0.65) | PI4KAPIK3CG | |
| SCHEMBL10288693 | 0.80 | PI4KA (0.57) | PI4KAPIK3CG | |
| SCHEMBL9952298 | 0.78 | PI4KA (0.57) | PI4KAPIK3CG | |
| SCHEMBL9954271 | 0.78 | PI4KA (0.68) | PI4KAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL9954117 | 0.78 | PI4KA (0.73) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |