Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9952097 | 0.74 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL9953097 | 0.71 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL30340329 | 0.66 | PIK3CD (0.63) | PIK3CD | |
| SCHEMBL9952257 | 0.66 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL29836162 | 0.66 | PIK3CD (0.47) | PIK3CD | |
| Hydrochloric Acid SCHEMBL9929198 | 0.65 | PIK3CD (0.46) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL9960928 | 0.65 | WHR1 (0.31) | — | |
| SCHEMBL9952487 | 0.64 | PIK3CD (0.43) | PIK3CD | |
| SCHEMBL9953231 | 0.64 | PIK3CD (0.36) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL19639730 | 0.64 | PIK3CD (0.48) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |