Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | LOX | P28300 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | NNMT | P40261 | 3/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281222 | 0.86 | NNMT (0.56) | KCNK3KCNK9LOXLOXL2NNMT | |
| SCHEMBL445784 | 0.86 | NNMT (0.56) | KCNK3KCNK9LOXLOXL2NNMT | |
| Hydrochloric Acid SCHEMBL7022071 | 0.84 | NNMT (0.54) | KCNK3KCNK9LOXLOXL2NNMT | |
| SCHEMBL9952643 | 0.84 | NNMT (0.54) | KCNK3KCNK9LOXLOXL2NNMT | |
| SCHEMBL27841468 | 0.82 | KCNK3 (0.52) | KCNK3KCNK9LOXLOXL2NNMT | |
| SCHEMBL12640026 | 0.80 | KCNK3 (0.55) | KCNK3KCNK9LOXLOXL2NNMT | |
| SCHEMBL229446 | 0.80 | KDM4C (0.57) | KCNK3KCNK9LOXLOXL2PROKR1 | |
| SCHEMBL29640109 | 0.80 | KCNK3 (0.55) | KCNK3KCNK9LOXLOXL2NNMT | |
| SCHEMBL29556902 | 0.80 | KDM4C (0.57) | KCNK3KCNK9LOXLOXL2PROKR1 | |
| SCHEMBL23539981 | 0.79 | PRSS1 (0.49) | KCNK3KCNK9LOXLOXL2NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655356-A1 | FAAH INHIBITORS | Ironwood Pharmaceuticals, Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088469-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |