Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | PKM | P14618 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954454 | 0.87 | MEN1 (0.41) | KMT2APKMMEN1CYP3A4CYP1A2 | |
| SCHEMBL9953607 | 0.81 | KMT2A (0.58) | KMT2APKMMEN1CYP3A4CYP1A2 | |
| SCHEMBL9954225 | 0.80 | ALDH1A1 (0.52) | KMT2AMEN1CYP3A4MAPTALDH1A1 | |
| SCHEMBL31241102 | 0.77 | CACNA2D1 (0.42) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL5791447 | 0.76 | CYP2D6 (0.53) | KMT2APKMMEN1CYP3A4CYP1A2 | |
| SCHEMBL6797484 | 0.74 | POLB (0.72) | KMT2AMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9955108 | 0.73 | MEN1 (0.40) | KMT2AMEN1CYP3A4ALDH1A1GAA | |
| SCHEMBL9145974 | 0.71 | GRK2 (0.56) | KMT2APKMMEN1CYP3A4CYP1A2 | |
| SCHEMBL9149104 | 0.71 | MEN1 (0.56) | KMT2APKMMEN1CYP3A4CYP1A2 | |
| SCHEMBL9954047 | 0.71 | HSD17B10 (0.41) | KMT2AMEN1CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |