Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | PKM | P14618 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954631 | 0.85 | KMT2A (0.46) | KMT2APKMMEN1CYP1A2CYP2D6 | |
| SCHEMBL14247363 | 0.83 | GABRA1 (0.52) | KMT2APKMMEN1CYP1A2CYP2D6 | |
| SCHEMBL9952928 | 0.81 | KMT2A (0.53) | KMT2APKMMEN1CYP1A2CYP2D6 | |
| SCHEMBL5791447 | 0.81 | CYP2D6 (0.53) | KMT2APKMMEN1CYP1A2CYP2D6 | |
| SCHEMBL9953464 | 0.78 | ALDH1A1 (0.57) | KMT2APKMMEN1CYP3A4RXFP1 | |
| SCHEMBL9954589 | 0.77 | ALOX12 (0.50) | KMT2AMEN1GABRA1GABRA5TBXAS1 | |
| SCHEMBL9145974 | 0.76 | GRK2 (0.56) | KMT2APKMMEN1CYP1A2CYP2D6 | |
| SCHEMBL9149104 | 0.76 | MEN1 (0.56) | KMT2APKMMEN1CYP1A2CYP2D6 | |
| SCHEMBL10289136 | 0.76 | CACNA2D1 (0.51) | KMT2AMEN1CYP1A2CYP2D6OPRM1 | |
| SCHEMBL9952969 | 0.75 | DPP4 (0.51) | KMT2AMEN1OPRM1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |