Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953017 | 0.88 | PI4KA (0.53) | PI4KAPIK3CGLMNAPOLBPIK3CA | |
| SCHEMBL30902109 | 0.88 | PI4KA (0.53) | PI4KAPIK3CGLMNAPOLBPIK3CA | |
| SCHEMBL742722 | 0.86 | PIK3CA (0.49) | PI4KAPIK3CGPOLBPIK3CAPIK3R1 | |
| SCHEMBL16996896 | 0.80 | ALPL (0.54) | LMNAPOLBTHRBTSHRHSD17B10 | |
| SCHEMBL740363 | 0.80 | MEN1 (0.61) | LMNAPOLBTHRBTSHRHSD17B10 | |
| SCHEMBL9953341 | 0.79 | ALPL (0.51) | PI4KAPIK3CGLMNAPOLBTSHR | |
| SCHEMBL16996888 | 0.79 | PIK3C3 (0.60) | PI4KAPIK3CGPOLBPIK3CAPIK3R1 | |
| SCHEMBL16996891 | 0.79 | PIK3C3 (0.60) | LMNAPOLBTHRBTSHRHSD17B10 | |
| SCHEMBL462714 | 0.77 | PIK3CA (0.59) | PI4KAPIK3CGPIK3CAPIK3R1MTOR | |
| SCHEMBL30333881 | 0.77 | PIK3CA (0.59) | PI4KAPIK3CGPIK3CAPIK3R1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |