Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.42 |
| ▸ | PI4KA | P42356 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953720 | 0.90 | ALPL (0.62) | ALPLPIK3CGPI4KAPOLBPIK3CA | |
| SCHEMBL798076 | 0.89 | ALPL (0.47) | ALPLPIK3CGPI4KAPIK3CAPIK3R1 | |
| SCHEMBL9952995 | 0.84 | LMNA (0.49) | ALPLPOLBLMNAPIK3CAPIK3CD | |
| SCHEMBL22447713 | 0.84 | PIK3CA (0.47) | ALPLPIK3CGPIK3CAPIK3R1PIK3CD | |
| SCHEMBL9954198 | 0.82 | ALPL (0.62) | ALPLPIK3CGPI4KAPOLBPIK3CA | |
| SCHEMBL29556110 | 0.81 | ALPL (0.55) | ALPLPIK3CGPI4KAPIK3CAPIK3R1 | |
| SCHEMBL110313 | 0.81 | ALPL (0.55) | ALPLPIK3CGPI4KAPIK3CAPIK3R1 | |
| SCHEMBL29434933 | 0.81 | ALPL (0.55) | ALPLPIK3CGPI4KAPIK3CAPIK3R1 | |
| SCHEMBL9953111 | 0.79 | PI4KA (0.47) | ALPLPIK3CGPI4KAPOLBLMNA | |
| SCHEMBL9955197 | 0.79 | ALPL (0.66) | ALPLPIK3CGPI4KAPOLBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |